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| Desired Industry: Biotech |
SpiderID: 8945 |
| Desired Job Location: Waltham, Massachusetts |
Date Posted: 9/27/2006 |
| Type of Position: Full-Time Permanent |
Availability Date: 10/16/06 |
| Desired Wage: 85,000 |
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U.S. Work Authorization: Yes |
| Job Level: Experienced with over 2 years experience |
Willing to Travel: Yes, Less Than 25% |
| Highest Degree Attained: Doctoral |
Willing to Relocate: No |
Objective:
A position that requires extensive knowledge and experience in the area of synthetic organic chemistry.
Experience:
Qualified by over 9 years of industrial experience and demonstrated results in:
„X Multistep Organic Synthesis
„X Solution-Phase Parallel Synthesis
„X Medicinal Chemistry
„X NMR, HPLC, Mass Spec.
„X Outsource Management
„X Scientific Training
PROFESSIONAL EXPERIENCE
MASSACHUSETTS GENERAL HOSPITAL, Boston, MA March 2005-present
Project Team Leader I, Center for Computational and Integrative Biology
Designed and synthesized novel mucolytic agents for asthma and cystic fibrosis sufferers.
JOHNSON MATTHEY PHARMA SERVICES, INC., Devens, MA 2004-2005
Principal Scientist, Medicinal Chemistry
Synthesized organic compounds for biotechnology and pharmaceutical clients.
THRASOS THERAPEUTICS, INC., Hopkinton, MA 2003 ¡V 2004
Senior Scientist, Medicinal Chemistry
Selected, synthesized, and formulated compounds designed to modulate protein-protein interactions.
ARQULE, INC., Woburn, MA 1998 ¡V 2003
Staff Investigator
Selected and optimized synthetic pathways for the automated parallel synthesis of solution-phase, organic compound arrays of medicinal relevance.
KEY SCIENTIFIC AND MANAGEMENT ACCOMPLISHMENTS
„X (Johnson Matthey Pharma Services, Inc) Custom synthesized complex benzodiazepine-based chemical entities for a client interested in autoimmune antagonists.
„X Helped launch a start-up biotech (Thrasos Therapeutics, Inc.) by providing scientific insight and synthesizing compounds pertinent to establishing the company¡¦s patented TheraLocTM platform.
„X Contributed novel parallel synthetic sequences for ArQule¡¦s Mapping Array Program (>35,000 personal compounds), which significantly expanded the breadth of the Program¡¦s compound archive.
„X Synthesized three ¡§focused¡¨ arrays for ArQule¡¦s Ion Channel Program, which provided > 1,100 novel, drug-like compounds for screening that increased the IC Program¡¦s overall credibility.
„X Managed 2 major outsourcing programs, which delivered valuable compounds and array procedures for far less than had they been done internally.
„X Supervised and trained scientists on two Varian 300 NMR instruments, which provided rapid access to essential spectral data without the need of hiring a full-time technician.
Postdoctoral Fellow, The State University of New York at Stony Brook 1996 ¡V 1998
Research Advisor: Professor Iwao Ojima
Selected and synthesized paclitaxel (Taxol) analogs to be used as analytical ¡§probes¡¨ for the elucidation of the bioactive conformation that is recognized by its ƒÒƒ{tubulin binding site.
Research Associate, Bristol Myers-Squibb, Lawrenceville, NJ 1988 ¡V 1991
Education:
Ph.D. (Organic Chemistry), Boston College 1991 ¡V 1996
Graduate Advisor: Professor T. Ross Kelly (natural product synthesis, heterocyclic chemistry, metal-catalyzed cross-coupling techniques)
B.A. (Chemistry, Honors), Rutgers College, New Brunswick, NJ 1984 ¡V 1988
Affiliations:
Member of the American Chemical Society since December, 1988.
Skills:
I am a synthetic organic chemist with over nine years of industrial experience. My areas of expertise include solution-phase parallel synthesis, multi-step organic synthesis (including insourced custom synthesis), and structure guided drug design. Currently, I am working with a research group at Massachusetts General Hospital, but I am hoping to return to industry. I have a proven track record of meeting company timelines, working effectively within team settings, and supervising and executing scientific creativity.
Reference:
1. Dr. Michael Sworin
Staff Member
MIT Lincoln Laboratory
Lexington, MA
781-981-3869
sworin@ll.mit.edu
2. Dr. Murty Bosukonda
Executive Director
Thrasos Therapeutics, Inc.
Hopkinton, MA
508-417-7202 (x104)
murty.bosukonda@thrasos.com
3. Dr. William Carlson
Chief Scientific Officer
Thrasos Therapeutics, Inc.
Hopkinton, MA
508-417-7202 (x107)
bill.carlson@thrasos.com
Candidate Contact Information:
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